Mortal Kombat: Shaolin Monks is a fighting game developed by Midway Games and published by Midway Games. It was released in 2005 for the PlayStation 2, Xbox, and GameCube consoles.

The PS2 ISO -USA- refers to the game's disc image file for the PlayStation 2 console, specifically the US version. This file can be used to play the game on a PC using a PlayStation 2 emulator or on a PlayStation 2 console using a modded device.

The game's storyline is set in the Mortal Kombat universe, but it does not follow the events of a specific Mortal Kombat game. Instead, it offers an alternate take on the characters and their motivations. The story revolves around the Shaolin Monks, a group of warriors who are on a quest to stop the evil forces of Shang Tsung.

To play Mortal Kombat: Shaolin Monks PS2 ISO -USA-, you will need a PlayStation 2 emulator or a modded PlayStation 2 console. Some popular emulators for playing PS2 games on PC include PCSX2 and DamonPS2.